Melting point

The BUCHI Melting Point M-560 is a compact benchtop instrument for accurate visual determination of melting, boiling and cloud points in accordance with European, USP and Japanese Pharmacopoeia methods. Three capillary samples are analysed simultaneously and observed through an integrated 2.5x magnifying viewer, with results shown on a high-resolution colour display and archived by an integrated video-recording function. The wide operating range from 10 to 400 °C covers virtually every organic and inorganic substance of interest to pharmaceutical, chemical and academic laboratories, while user-selectable heating rates allow the operator to balance throughput against accuracy for routine identity checks or for high-precision reference substance characterisation. Real-time video capture lets operators review the transition retrospectively, share results with reviewers and archive full documentation for quality assurance. The intuitive interface, minimal consumable requirements (standard glass capillaries) and rapid heat-up/cool-down cycles make the M-560 an efficient choice for QC benches that run dozens of samples per day, and its compact footprint fits easily into small teaching or R&D labs.

Key specifications:

• Temperature range: 10 to 400 °C

• Sample capacity: 3 capillaries in parallel

• Detection method: visual (operator observation)

• Integrated 2.5x magnifying viewer

• Large high-resolution colour display

• Video recording of the phase transition for documentation

• Fully compliant with European, USP and Japanese Pharmacopoeia methods

Applications:

• Pharmaceutical identity and purity testing

• QC of chemical substances and synthetic intermediates

• Academic teaching and research

• Food quality control (fats, slip melting point)

• Reference substance characterisation

The BUCHI Melting Point M-565 is a fully automatic melting point apparatus that combines pharmacopoeia-compliant measurement with digital image processing for objective, reproducible results. Automatic detection of melting, boiling and cloud points removes operator subjectivity, while integrated video recording preserves the complete thermal event for documentation and audit trails - ideal for regulated pharmaceutical QC environments. Up to three capillary samples are analysed in parallel across a 10 to 400 °C range, supporting both rapid identity screening and high-precision certification work on the same instrument. The high-resolution colour display and 2.5x magnifier let the operator confirm the automatic reading visually, and the optional Sample Loader M-569 automates capillary filling to further reduce variability and manual effort. Full compliance with European, USP and Japanese Pharmacopoeia methods makes the M-565 the reference instrument for GMP identity testing, method validation and stability studies in modern pharmaceutical, contract-research and fine-chemical laboratories. Because the entire measurement is recorded on video, results can be reviewed, re-evaluated or audited long after the sample is discarded, supporting traceability requirements and reducing the need to repeat measurements.

Key specifications:

• Temperature range: 10 to 400 °C

• Sample capacity: 3 capillaries analysed in parallel

• Detection method: fully automatic via digital image analysis

• Video recording of the entire measurement

• Optional Sample Loader M-569 for automated capillary filling

• Large high-resolution colour display with 2.5x magnifier

• Fully compliant with European, USP and Japanese Pharmacopoeia methods

Applications:

• Regulated pharmaceutical QC (GMP identity testing)

• Contract research and academic laboratories

• Fine chemical and specialty compound characterisation

• Method validation and stability studies

• Objective purity assessment of new chemical entities