With the Mini Spray Dryer S-300 you can benefit from the highest possible automation levels to improve your process efficiency and free more time for your formulations. The Mini Spray Dryer S-300 allows you to achieve highly reproducible results, speed up the optimization of your formulation and simplify upscaling applications.
The SiccaDania Small Scale Spray Dryers provide high-quality products at a smaller scale. Therefore, they allow our customers to innovate and experiment on a small scale before upscaling.

The BUCHI Mini Spray Dryer S-300 is a fully automated laboratory spray dryer for producing fine powders in R&D, formulation and process development. It handles aqueous, organic and corrosive feeds and produces particles across a wide size range with a high yield thanks to its coated cyclone and optimized gas flow. Auto Mode automates heating, conditioning and shutdown, while remote monitoring and method programming via the mobile app and PC keep runs reproducible and hands-off.
Key specifications:
• Inlet temperature: up to 220 °C (Advanced) or 250 °C (Corrosives)
• Evaporation capacity: up to 1.0 L/h H₂O (higher with organic solvents)
• Particle size range: 1 – 60 μm
• Yield: up to 70 %
• Feed compatibility: water, organic solvents, acids and alkalines (Corrosives model)
• Nozzles: two-fluid, three-fluid and ultrasonic
• Auto Mode with method programming and sample queue
• Real-time inlet, outlet and product temperature monitoring
• PDF / CSV reporting, mobile app remote control
Available models:
• S-300 Basic — aqueous formulations
• S-300 Advanced — aqueous and organic solvents (with Inert Loop S-395 option)
• S-300 Corrosives — acids, alkalines and mixed feeds
Applications:
• Pharmaceutical solid dispersions and inhalable drugs
• Food and nutraceutical encapsulation (vitamins, probiotics, flavors)
• Cosmetics and fragrance formulation
• Battery electrode and catalyst materials
• Nano-material and chemical process development

Small Scale Spray Dryers
The SiccaDania Small Scale Spray Dryers provide high-quality spray dryers for both R&D and production. The small scale spray dryers allow customers to innovate and experiment on a small scale before upscaling to full scale production spray dryers.
All SiccaDania small scale spray dryers are available as standard plants. Furthermore, the spray dryers can be designed based on a modular concept with a range of optional items. In this way, each individual plant can be custom designed to match our customers’ individual requirements. The spray drying process is scalable and the SiccaDania Small scale spray dryers are available in many flexible configurations enabling process simulations of larger industrial size spray dryers.
The SiccaDania small scale spray dryers are provided in either a single stage or a multi stage configuration.
Premium quality laboratory equipment and services.