HPLC
KNAUER HPLC:
KNAUER manufactures high-end scientific instruments for research, routine analysis, quality assurance, and other applications. Supported technologies include liquid chromatography, precise handling and pumping of liquids up to high pressures, as well as flow-through detection of dissolved substances. Customizable products and solutions are one of our strengths. Made in Germany.
Developing devices that help people in the laboratory to gain new insights or facilitate their work. This is the spirit in which KNAUER was founded and continues to drive the company today.
The analytical HPLC, ULDC and UHPLC systems of the KNAUER AZURA® liquid chromatography family are designed to support and facilitate your work. Whether doing routine analysis or demanding separation tasks, AZURA systems are the right tool to overcome your analytical challenges. Choose between different gradient forming technologies at various back pressure ranges to find the best configuration for your task.
Nearly every chromatographer around the world is facing the problem of unresolved peak pairs or groups. In many cases, the separation achieved with modern HPLC, UHPLC, and core-shell columns is destroyed by an excessive peak dispersion due to an inappropriate extra column volume.
Ultra Low Dispersion Chromatography (ULDC) is the one and only key to overcome this common problem for every HPLC and UHPLC user. The maximum separation power of every column with its sharpest peaks possible can be accomplished by ULDC.
The new KNAUER AZURA 862 chromatography systems meet the enormous requirements that are essential to minimize the extra column volume and thus the peak dispersion. With this, ULDC with the KNAUER AZURA 862 systems is the new gold standard in chromatography superseding HPLC and UHPLC.
Complete solutions for FPLC (Fast Protein Liquid Chromatography) on a small footprint: AZURA® FPLC systems combine flexibility and reliability. The AZURA® FPLC is the perfect choice for your protein purification task.
Design your AZURA Bio purification system to your needs. Multiple functionalities such as automatic sample injection via autosampler, column switching, buffer and sample selection as well as fraction collection enable the user to automate the purification process.
A range of different detectors let you keep track of your target molecules. A wide flow rate range and compatibility with columns from all vendors offer maximum flexibility. The intuitive software PurityChrom® combines all the advantages of a versatile purification software.
The general objective of preparative chromatography is to isolate, purify and collect your target compounds. Preparative applications are often initially performed on an analytical level and need to be upscaled.
Depending on the desired scale, the requirements for a preparative system differ in eluent supply, sample injection, column, and detection.
We customize our systems to meet your chromatography scale-up and purification requirements. Benefit from our experience in preparative chromatography. Adaptable AZURA® preparative LC systems are the perfect solution for frequently changing separation tasks – from milligram to kilogram scale.
Design your preparative HPLC system to your needs and combine flexibility and reliability. The Preparative LC systems are tailor-made for you.
AZURA® SEC is KNAUER's line of GPC and SEC systems that offer solutions for different applications and labs. These systems can analyze, separate and fractionate sample components based on size and molecular weight, making them useful for industries such as polymer, food, biochemistry, and pharmaceuticals, as well as research.
The systems come in different variants, each tailored to specific lab needs, such as the AZURA SEC Compact for budget-friendly solutions or the AZURA SEC Lab for highest analytical performance.
Simulated moving bed chromatography (SMBC) is increasingly applied as a separation technique in the pharmaceutical industry, production of fine chemicals, and in the field of bioengineering.
SMB is a multi-column method in process chromatography that enables substance mixtures to be continuously separated and extracted in two fractions. Its efficiency is significantly higher than batch chromatography, through better utilization of the column stationary phase.
Although in principle limited to two fraction separations, each partial fraction can be separated into further fractions by repeated use of the SMB process – down to binary substance mixtures.
Typically, the SMB process is used for two component mixtures, like chiral separations or mixtures with a "leading" or a "trailing" key product peak in the chromatogram.
This dedicated system is specifically designed for solid phase extraction (SPE) in combination with a powerful analytical KNAUER AZURA HPLC system.
Our versatile Assistant Module ASM 2.2L with two switching valves V 4.1 and a pump P 4.1S enables an efficient online SPE to concentrate analytes prior to HPLC analysis. This results in the reduction of analysis time and sample contamination as well as in an increase of analyte yield.
Subsequently, separation and analysis can be achieved with a classical KNAUER AZURA analytical system equipped with P 6.1L LPG pump, a column thermostat CT 2.1 and a multi-wavelength detector MWD 2.1L to detect up to eight different wavelengths simultaneously.
KNAUER´s analytical HPLC system portfolio Sensitive, precise and adaptable to your needs. The analytical HPLC, ULDC and UHPLC systems of the KNAUER AZURA® liquid chromatography family are designed to support and facilitate your work. Whether doing routine analysis or demanding separation tasks, AZURA systems are the right tool to overcome your analytical challenges. Choose between different gradient forming technologies at various back pressure ranges to find the best configuration for your task.