Homogenizers

The Genizer UltraGenizer is a laboratory ultra-high-pressure processing device — an electrically driven, benchtop high-shear homogenizer that requires no compressed air or hydraulic oil to reach a maximum operating pressure of 4,200 bar (60,000 psi), making it a high-shear liquid homogenizer suited to lipid nanoparticle preparation. It is energy efficient — about half the energy loss of most homogenizers — with a small, integrated, lightweight design and a smart programming control system offering ±0.1 mL controlled inlet volume plus auto-stop by time or volume, delivering more than 150 mL/min at 60,000 psi in silent, CE-compliant operation across six pressure variants from 20,000 to 60,000 psi.

Key features:

• Electrically driven benchtop homogenizer reaching 4,200 bar (60,000 psi)

• No compressed air or hydraulic oil required for operation

• Flow rates from 12 to 35 L/hr across six pressure variants (20,000–60,000 psi)

• ±0.1 mL controlled inlet volume with auto-stop by time or volume

• Energy-efficient, silent operation with configurable syringe and reservoir options

Typical applications:

• Lipid nanoparticle and liposome preparation

• Nanoemulsions, nanodispersions and graphene processing

• Deagglomeration requiring ultra-high shear forces

NanoGenizer is a laboratory high pressure processing device. It is an electrically-driven and bench-top, high pressure homogenizer requiring no compressed air or hydraulic oil to achieve maximum 3,062 bar (45,000 psi) operating pressure.

NanoGenizer high pressure homogenizer is composed of a feed reservoir, high pressure pump, transducer, PLC control panel and microfluidics diamond interaction chamber. The sanitary pump system of the NanoGenizer high pressure homogenizer is able to supply the desired pressure to the product stream and push it through the micron chamber (microreactor) to create high shear rates and strong impact within the stream. This process results in uniform particle distribution and smaller particle sizes.

Application of NanoGenizer High Pressure Homogenizer:

Cell disruption and particle size reductionNanoemulsions Nano dispersionsLiposomesDeagglomeration 

Performance of NanoGenizer High Pressure Homogenizer:

Energy efficient, 1/2 energy loss of the most homogenizersSmall (integrated design delivers the light weight and small dimensions)Smart (programming control systems confer diligent functions: controlled inlet volume ± 0.1mL; auto stop with time/volume)Silent (noiseless performance)Strong (more than 150 mL/min at 30,000 psi)CE compliant and RoHS compliant

The Genizer MixGenizer is a high-pressure homogenizer designed specifically for mixing and homogenizing sample fluids fed from two or more inlet ports through a diamond mixing chamber, reaching pressures up to 30,000 psi with a flow rate over 240 mL/min. It is energy efficient — about half the energy loss of most homogenizers — with a small, integrated design and a smart programming control system offering ±0.1 mL controlled inlet volume plus auto-stop by time or volume, all in silent, CE- and RoHS-compliant operation. A minimum sample size of 5 mL and configurable syringe sizes (20–200 mL), inlet cylinders and heat exchangers let the MixGenizer be tailored to specific multi-stream mixing processes.

Key features:

• Diamond mixing chamber for two or more inlet streams, up to 30,000 psi

• Flow rate over 240 mL/min at maximum pressure

• Minimum sample volume 5 mL, configurable syringe sizes 20–200 mL

• ±0.1 mL controlled inlet volume with auto-stop by time or volume

• CE and RoHS compliant; silent, energy-efficient operation

Typical applications:

• Multi-stream nanodispersion, nanoemulsion and nanotube mixing

• Cell disruption and micro/nanoencapsulation in polymers, liposomes and oils

• Solid dispersion, suspension and deagglomeration requiring multi-port mixing

The Genizer PilotGenizer is a pilot-scale high-pressure homogenizer with dual pumps for continuous-pressure operation up to 45,000 psi, offered in seven pressure variants from 15,000 to 45,000 psi with flow rates from 20 to 60 L/hr. It is energy efficient — about half the energy loss of most homogenizers — with a small integrated design, smart programmable controls and silent, high-efficiency operation delivering more than 30 L/hr at 30,000 psi. The system is CE and RoHS compliant, runs on 380/480 V power, is rated to 80°C, and uses flush-to-clean or CIP cleaning, bridging the gap between laboratory-scale nanoprocessing and full production.

Key features:

• Dual-pump, continuous-pressure design across seven variants (15,000–45,000 psi)

• Flow rate from 20 to 60 L/hr depending on pressure setting

• Energy-efficient — about half the energy loss of most homogenizers

• CE and RoHS compliant; flush-to-clean or CIP cleaning

• 380/480 V power supply, rated to 80°C

Typical applications:

• Pilot-scale nanodispersions, nanoemulsions, nanotubes and graphene processing

• Cell disruption and micro/nanoencapsulation in polymers, liposomes and oils

• Scale-up bridge between laboratory R&D and production

The Genizer NanoGenizer-Quad is a laboratory quad-pump high-pressure homogenizer testing up to 30,000 psi with electric power, using a parallel and series flow-direction concept. It is energy efficient — losing only about half the energy of most homogenizers — and combines a small, integrated design with a smart programming control system offering auto-stop by time or volume, silent operation and a strong flow rate of 6–22 L/hr. The system is CE and RoHS compliant, uses a 500 mL stainless-steel inlet reservoir with Tri-Clamp connections, and reaches a maximum pressure of 30,000 psi at temperatures up to 80°C, making it suitable for GMP-ready laboratory use.

Key features:

• Quad-pump design testing up to 30,000 psi with parallel/series flow direction

• Flow rate 6–22 L/hr, minimum sample volume 5 mL

• Energy-efficient — around half the energy loss of most homogenizers

• Touch-screen programming control with auto-stop by time, volume, pressure or temperature

• CE and RoHS compliant, Tri-Clamp inlet/outlet, 316L stainless product contact parts

Typical applications:

• Nanodispersions, nanoemulsions and nanotube processing

• Cell disruption and micro/nanoencapsulation in polymers, liposomes and oils

• Solid dispersion, suspension and deagglomeration

The Genizer NanoGenizer-Dual is a portable laboratory dual-pump high-pressure homogenizer testing up to 30,000 psi with electric power. It is energy efficient — about half the energy loss of most homogenizers — and combines a small, integrated, lightweight design with a smart programming control system offering auto-stop by time or volume and silent, noiseless operation. Flow rate reaches 180 mL/min at 25,000 psi and 120 mL/min at 30,000 psi from a minimum 5 mL sample, and the system is CE and RoHS compliant, rated to a maximum temperature of 80°C, with configurable pressure (15,000–30,000 psi), syringe sizes and optional heat exchangers to suit specific process needs.

Key features:

• Dual-pump design testing up to 30,000 psi, portable benchtop footprint

• Flow rate 180 mL/min at 25,000 psi, 120 mL/min at 30,000 psi

• Minimum sample volume 5 mL; configurable syringe sizes 10 mL–200 mL

• Smart touch-screen control with auto-stop by time/volume, silent operation

• CE and RoHS compliant; optional inlet reservoirs and heat exchangers

Typical applications:

• Nanodispersions, nanoemulsions and nanotube processing

• Cell disruption and micro/nanoencapsulation in polymers, liposomes and oils

• Solid dispersion, suspension and deagglomeration

The Genizer NanoGenizer-Titanium is a portable laboratory high-pressure homogenizer with electric drive, testing up to 45,000 psi and delivering more than 150 mL/min at 30,000 psi. It is energy efficient — only about half the energy loss of most homogenizers — with a small, integrated, lightweight design and a smart programming control system offering precise ±0.1 mL controlled inlet volume plus auto-stop by time or volume. Operation is silent and CE and RoHS compliant, with seven pressure variants from 15,000 to 45,000 psi, a minimum sample size of just 2 mL, and configurable syringe sizes, inlet cylinders and heat exchangers to match specific process requirements.

Key features:

• Electric-drive laboratory homogenizer testing up to 45,000 psi

• Flow rate over 150 mL/min at 30,000 psi across seven pressure variants

• Minimum sample volume of just 2 mL

• Precise ±0.1 mL controlled inlet volume with auto-stop by time/volume

• CE and RoHS compliant; silent, energy-efficient operation

Typical applications:

• Nanodispersions, nanoemulsions and nanotube processing

• Cell disruption and micro/nanoencapsulation in polymers, liposomes and oils

• Solid dispersion, suspension and deagglomeration

The Genizer HandGenizer is a portable, hand-driven high-pressure homogenizer for concept testing up to 30,000 psi, offering a low-cost alternative to compressed-air-driven high-pressure homogenizers. Its lightweight, small-footprint design allows convenient hand operation without any need for compressed gas, making it a practical choice for small-scale formulation screening, and it can double as a high-pressure pump for sanitary applications such as liposome extrusion. Pressure builds through an adjustable three-stage system — 10,000 psi, 20,000 psi and 30,000 psi — with flow rates from 25 to 50 mL/min depending on the target pressure, using a diamond interaction chamber for consistent particle-size reduction.

Key features:

• Hand-driven operation — no compressed gas or electricity required

• Adjustable three-stage pressure: 10,000 / 20,000 / 30,000 psi

• Flow rate 25–50 mL/min depending on pressure stage

• Diamond interaction chamber for consistent particle-size reduction

• Portable, lightweight design for benchtop concept testing

Typical applications:

• Small-scale formulation screening and concept testing

• Nanodispersions, nanoemulsions and nanotube processing

• Cell disruption and micro/nanoencapsulation in polymers, liposomes and oils

The Genizer ManuGenizer is a manufacturing-scale, dual-pump high-pressure homogenizer designed to deliver constant pressure of up to 30,000 psi to the product stream, reducing processing time and maximizing microfluidic homogenizing performance. It uses a microfluidics diamond interaction chamber with multi-slotted nano-size micro-channels, allowing much larger volumes to be processed continuously at more than 480 L/hr at 30,000 psi. The system provides reproducible submicron particle-size distribution, a smart anti-clogging backflush system, and a programmable, user-friendly control interface, with compliance support for IQ/OQ, FAT/CIP/SIP audit and cGMP standards, and is CE and RoHS compliant.

Key features:

• Dual-pump design delivering constant pressure up to 30,000 psi

• Microfluidic diamond interaction chamber with nano-size micro-channels

• Continuous throughput of more than 480 L/hr at 30,000 psi

• Reproducible submicron particle-size distribution

• Smart anti-clogging backflush system; IQ/OQ, FAT/CIP/SIP and cGMP compliance support

Typical applications:

• Manufacturing-scale nanoemulsion and liposome production

• Cell disruption (E. coli, yeast and other microorganisms)

• Continuous nanodispersion, deagglomeration and micro/nanoencapsulation processes

The Genizer ProdGenizer is a production-scale high-pressure homogenizer with dual pumps for continuous operation at pressures up to 45,000 psi, available in 5,000–30,000 psi model variants delivering flow rates from 100 to 300 L/hr. It is energy efficient — about half the energy loss of most homogenizers — with a small integrated design, smart programming controls and silent, high-efficiency operation. The system is CE and RoHS compliant with FDA 21 CFR, IQ/OQ, explosion-proof and CIP options available, runs on 380–480 V three-phase power, and is rated to 80°C, making it suited to full production-scale nanoemulsion and homogenization processes.

Key features:

• Dual-pump, continuous-pressure design up to 45,000 psi

• Model range delivers 100–300 L/hr flow rate depending on pressure (5,000–30,000 psi)

• Energy-efficient — about half the energy loss of most homogenizers

• Optional FDA 21 CFR, IQ/OQ, explosion-proof and CIP compliance

• 380–480 V three-phase power; flush-to-clean or CIP cleaning

Typical applications:

• Production-scale nanodispersions, nanoemulsions, nanotubes and graphene processing

• Cell disruption and micro/nanoencapsulation in polymers, liposomes and oils

• Solid dispersion, suspension and deagglomeration at industrial scale