TimsTOF fleX

The Bruker timsTOF fleX is a dual-source instrument that combines full ESI functionality for Omics workflows with an integrated MALDI source for fast MALDI imaging on a single platform. MALDI-guided SpatialOMx pairs the regiospecificity of MALDI imaging with PASEF-empowered Omics, so high identification rates are achievable from very small sample amounts. Bruker's microGRID technology combines the MALDI stage with smartbeam 3D laser positioning to deliver high-resolution imaging down to 5 micrometre spatial resolution, integrated directly into Bruker's automated SCiLS imaging workflows.

Key features:

• Dual-source design: full ESI plus integrated MALDI on one instrument

• SpatialOMx workflow combines MALDI imaging regiospecificity with PASEF Omics

• microGRID technology for imaging down to 5 um spatial resolution

• Fully integrated into Bruker's automated SCiLS imaging software

• Robust ESI measurements alongside spatially resolved tissue analysis

Typical applications:

• Spatial multi-omics directly from tissue sections

• High-resolution MALDI imaging combined with LC-MS Omics

• Proteomics, metabolomics and lipidomics from small sample amounts