Bruker TimsTOF SCP

Bruker's timsTOF SCP platform is built for 4D-Proteomics at the single-cell and low-sample-amount scale, reaching up to 300 Hz PASEF speed with near-100% ion capture efficiency for exceptional sensitivity and proteome depth. Smart ion transfer through the Athena Ion Processor and an optimised CaptiveSpray Ultra 2 source keeps the spray stable and ion transfer efficient even at very low sample loads. MOMA (Mobility Offset, Mass Aligned) separates co-eluting isobaric ions in the mobility dimension for higher specificity, while CCS-enabled scoring tools such as TIMScore and DIA-NN 4D-Proteomics support confident identification even at low signal-to-noise ratios.

Key features:

• Up to 300 Hz PASEF speed with near-100% ion capture efficiency

• Athena Ion Processor and CaptiveSpray Ultra 2 for stable low-flow ion transfer

• MOMA technology separates co-eluting isobaric ions in the mobility dimension

• CCS-enabled TIMScore and DIA-NN 4D-Proteomics support for low-abundance identification

• Upgradable platform designed to keep pace with future method development

Typical applications:

• Single-cell and ultra-low sample amount proteomics

• High-confidence identification of low-abundance peptides

• 4D-Proteomics research requiring maximum sensitivity